Avian Influenza A H5N1 Virus

作者：Loeffelholz Michael J^*

来源：Clinics in Laboratory Medicine, 2010, 30(1): 1-+.

DOI：10.1016/j.cll.2009.10.005

• Influenza
• Avian influenza A H5N1 virus
• Diagnosis
• Epidemiology

Although influenza A viruses of avian origin have long been responsible for influenza pandemics, including the "Spanish flu" pandemic of 1918, human infections caused by avian subtypes of influenza A virus, most notably H5N1, have emerged since the 1990s (H5N1 in 1997; H9N2 in 1999; and H7N7 in 2003). The wide geographic distribution of influenza A H5N1 in avian species, and the number and severity of human infections are unprecedented. Together with the ongoing genetic evolution of this virus, these features make influenza A H5N1 a likely candidate for a future influenza pandemic. This article discusses the epidemiology, pathogenesis, and diagnosis of human infections caused by influenza A H5N1 virus.

• 出版日期2010-3