A Case of Idiopathic Systemic Capillary Leak Syndrome with High Serum Levels of G-CSF on Exacerbation

作者:Nakagawa Naoki*; Ota Hisanobu; Tanabe Yasuko; Kabara Maki; Matsuki Motoki; Chinda Junko; Sakamoto Naka; Fujino Takayuki; Takehara Naofumi; Takeuchi Toshiharu; Kawabe Jun ichi; Sato Nobuyuki; Kawamura Yuichiro; Fukuhara Takashi; Ikuta Katsuya; Kikuchi Kenjiro; Hasebe Naoyuki
来源:Internal Medicine, 2011, 50(6): 597-600.
DOI:10.2169/internalmedicine.50.4857

摘要

Systemic capillary leak syndrome (SCLS) is a life-threatening disorder which presents with periodic episodes of hypovolemic shock, due to plasma leakage to the extra-vascular space reflected by accompanying hypoalbuminemia, hemoconcentration and edema often with associated monoclonal gammopathy. We describe a 28-year-old woman with SCLS who required aggressive fluid resuscitation and was successfully treated with corticosteroid, terbutaline, and theophylline. At exacerbation, the levels of serum granulocyte colony-stimulating factor (G-CSF) were increased. Thus, G-CSF might play an important role and can be a useful biomarker for the severity of attacks in SCLS.

  • 出版日期2011