Measurements of wavelength dependent scattering and backscattering coefficients by low-coherence spectroscopy

作者：Bosschaart Nienke^*; Faber Dirk J; van Leeuwen Ton G; Aalders Maurice C G

来源：Journal of Biomedical Optics, 2011, 16(3): 030503.

DOI：10.1117/1.3553005

• spectroscopy
• scattering
• backscattering
• coherence
• tissues
• Mie theory

Quantitative measurements of scattering properties are invaluable for optical techniques in medicine. However, noninvasive, quantitative measurements of scattering properties over a large wavelength range remain challenging. We introduce low-coherence spectroscopy as a noninvasive method to locally and simultaneously measure scattering mu(s) and backscattering mu(b) coefficients from 480 to 700 nm with 8 nm spectral resolution. The method is tested on media with varying scattering properties (as = 1 to 34 mm(-1) and mu(b) = 2.10(-6) to 2.10(-3) mm(-1)), containing different sized polystyrene spheres. The results are in excellent agreement with Mie theory.

• 出版日期2011-3