ASSESSMENT OF CAROTID INTIMA-MEDIA THICKNESS IN ANKYLOSING SPONDYLITIS PATIENTS

作者：Ozsahin Mustafa^*; Buyukkaya Ramazan; Besir Fahri Halit; Uslu Mustafa; Demirin Hilmi; Baltaci Davut; Kutlucan Ali; Ermis Fatih; Ataoglu Safinaz; Erdogmus Besir

来源：Acta Medica Mediterranea, 2013, 29(4): 687-691.

• Ankylosing spondylitis
• carotid intima-media thickness
• atherosclerosis

Background and aim: Measurement of the intima media thickness (IMT) of the common carotid artery has been a useful index to identify premature atherosclerosis. In the present study, we aimed to compare the carotid IMT of ankylosing spondylitis (AS) patients with that of controls matched for age and sex. We also evaluated the risk factors for atherosclerosis related to AS.
Patients and methods: Fifty-five patients with AS and 55 healthy controls were included in the study. All of the patients underwent a clinical evaluation that included the following: Bath AS Disease Activity Index (BASDAI), Bath AS Functional Index (BASFI). Bath AS Patient Global Score (BAS-G), chest expansion, and modified Schober test. The same radiologist performed IMT measurements.
Results: The mean carotid IMT was 0.59 +/- 0.15 mm in patients and 0.50 +/- 0.10 nun in controls (p=0.001). Disease duration, Schober index, and chest expansion were correlated with risk of atherosclerosis in the patients with AS (r=0.301, r=-0.369, and r=0.511, respectively). Otherwise, BASDAI, BASFI, BAS-G, ESR, hsCRP and treatment seemed to have no effect on CIMT.
Conclusion: Our study shows that CIMT was significantly greater in the AS patients than in the controls paired for age and sex.

• 出版日期2013