Nickel-catalyzed C(sp2)-H selenation of imidazo[1,2-α]pyridines with arylboronic acids or alkyl reagents using selenium powder

作者：Zhu, Jie; Zhu, Wenhui; Xie, Ping; Pittman, Charles U., Jr.; Zhou, Aihua^*

来源：Tetrahedron, 2018, 74(45): 6569-6576.

DOI：10.1016/j.tet.2018.09.037

• Selenium
• C-Se bond
• Nickel-catalyzed
• C-H functionalization
• Arylboronic acid

A novel and efficient Ni-catalyzed aryl- and alkyl-selenation of imidazo[1,2-alpha]pyridines employing selenium powder has been developed for the first time. The significant advantages of this protocol are that it is an inexpensive nickel catalyst and exhibits broad functional-group compatibility and good reaction yields.

• 出版日期2018-11-8
• 单位江苏大学