Abscopal Effects and Yttrium-90 Radioembolization

作者:Ghodadra Anish; Bhatt Sumantha; Camacho Juan C; Kim Hyun S*
来源:CardioVascular and Interventional Radiology, 2016, 39(7): 1076-1080.
DOI:10.1007/s00270-015-1259-0

摘要

We present the case of an 80-year-old male with squamous cell carcinoma with bilobar hepatic metastases who underwent targeted Yttrium-90 radioembolization of the right hepatic lobe lesion. Subsequently, there was complete regression of the nontargeted, left hepatic lobe lesion. This may represent the first ever reported abscopal effect in radioembolization. The abscopal effect refers to the phenomenon of tumor response in nontargeted sites after targeted radiotherapy. In this article, we briefly review the immune-mediated mechanisms responsible for the abscopal effect.

  • 出版日期2016-7