An improved fiber tracking algorithm based on fiber assignment using the continuous tracking algorithm and two-tensor model

作者：Zhu, Liuhong; Guo, Gang^*

来源：Neural Regeneration Research, 2012, 7(21): 1667-1674.

DOI：10.3969/j.issn.1673-5374.2012.21.010

• two-tensor model
• fiber assignment by continuous tracking
• fiber tracking
• axonal injury
• demyelinating disease
• diffusion tensor imaging
• neural regeneration

This study tested an improved fiber tracking algorithm, which was based on fiber assignment using a continuous tracking algorithm and a two-tensor model. Different models and tracking decisions were used by judging the type of estimation of each voxel. This method should solve the cross-track problem. This study included eight healthy subjects, two axonal injury patients and seven demyelinating disease patients. This new algorithm clearly exhibited a difference in nerve fiber direction between axonal injury and demyelinating disease patients and healthy control subjects. Compared with fiber assignment with a continuous tracking algorithm, our novel method can track more and longer nerve fibers, and also can solve the fiber crossing problem.

• 出版日期2012-7
• 单位福建医科大学; 厦门市第二医院