A practice-based randomised controlled trial of the efficacy of three interventions to reduce dentinal hypersensitivity

作者：Gibson M; Sharif M O; Smith A; Saini P; Brunton P A^*

来源：Journal of Dentistry, 2013, 41(8): 668-674.

DOI：10.1016/j.jdent.2013.06.003

• Randomised controlled trial
• Dental practice
• Dentinal hypersensitivity
• Dentine bonding agent
• Desensitising toothpaste

Objectives: The aim of this study was to evaluate the efficacy of three different interventions (non-desensitising toothpaste, desensitising toothpaste and professionally applied dentine bonding agent) in reducing dentinal hypersensitivity over a 2-week, 3-month and 6-month-period in a dental practice setting.
Methods: This was a randomised controlled, single-blind; parallel-group trial conducted in general dental practice by a single general dental practitioner. Seventy-five subjects were randomly allocated to three groups; non-desensitising toothpaste (NDT), desensitising toothpaste (DT) and professionally applied desensitising agent (DA). Dentinal hypersensitivity was measured using a Visual Analogue Scale (VAS) to record the response from a standardised short blast of air from a triple syringe. Dentinal hypersensitivity was recorded at baseline, two weeks, three months and six months for all groups.
Results: Dentinal hypersensitivity reduced significantly (p < 0.0001) in both groups DT and DA, in addition the reduction in sensitivity was sustained and continued to improve over a 6-month-period. The greatest reduction in dentinal hypersensitivity was recorded in group DA.
Conclusions: The results from this study suggest that application of dentine bonding agents, to teeth diagnosed with dentine hypersensitivity provides the greatest improvement in dentine hypersensitivity at 2 weeks and 6 months. This reduction in dentine hypersensitivity is greater than that achieved by the desensitising toothpaste tested and a non-desensitising toothpaste.

• 出版日期2013-8