Bone scanning with sodium F-18-fluoride PET and PET/CT - German guideline Version 1.0

作者：Hellwig D^*; Krause B J; Schirrmeister H; Freesmeyer M

来源：Nuklearmedizin, 2010, 49(5): 195-201.

DOI：10.3413/nukmed-0343

• Guideline
• sodium F-18-fluoride
• PET
• PET/CT
• bone scanning
• skeletal imaging

In nuclear medicine, bone scanning is based on the principle of scintigraphy using bone-seeking radiopharmaceuticals which accumulate in sites of increased bone formation. From a historical point of view, F-18-fluoride was one of the first osteotropic tracers which was replaced by Tc-99m-labelled polyphosphonates. With the development of modern PET equipment the superior diagnostic performance of F-18-fluoride PET for the detection and characterization of osseous lesions was proven in comparison to conventional bone scanning. Recently, its importance as a substitute of conventional skeletal scintigraphy increased in a time with limited availability of Mo-99/Tc-99m. To ensure health care during this period, F-18-fluoride PET currently became part of common outpatient care.
This guideline comprehends recommendations on indications, protocols, interpretation and reporting of F-18-fluoride PET and PET/CT.

• 出版日期2010