Molecularly imprinted polymer grafted paper-based method for the detection of 17β-estradiol

作者：Xiao, Lei; Zhang, Zhen; Wu, Chuanchen; Han, Liying; Zhang, Hongyan^*

来源：Food Chemistry, 2017, 221: 82-86.

DOI：10.1016/j.foodchem.2016.10.062

• 17 beta-Estradiol
• Molecularly imprinted polymer
• Paper-based method

17 beta-estradiol (17 beta-E-2) usually is used to promote the growth of animal. Abuse of 17 beta-E-2 has become a global food security problem, because the residues in foods can cause endocrine disorder through the food chain. A novel molecularly imprinted polymer (MIP) grafted paper-based method for the sensitive and specific detection of 17 beta-E-2 was reported in this work. Results showed that the MIP's optimum synthetic conditions were as follows: 12 mL of acetonitrile was chosen as the solvent; the molar ratio of template molecule, functional monomer and cross linker was 1:12:12. MIP synthesized had a good recognition ability, the limit of detection (LOD) of established detection method for milk and human urine samples could reach 0.25 mu g L-1.

• 出版日期2017-4-15
• 单位山东师范大学