Developing NKT cells need their calcium

作者:Godfrey Dale I*; Stankovic Sanda; Baxter Alan G
来源:Nature Immunology, 2009, 10(3): 231-233.
DOI:10.1038/ni0309-231

摘要

Although the development of natural killer T cells is a T cell antigen receptor-dependent process, the signaling pathways involved are poorly defined. New data demonstrate that the calcineurin-transcription factor NFAT pathway exerts a critical influence on this process by controlling the transcription factor Egr2.

  • 出版日期2009-3