A cysteamine-selective two-photon fluorescent probe for ratiometric bioimaging

作者:Sarkar Avik R; Heo Cheol Ho; Kim Eunjin; Lee Hyo Won; Singh Hardev; Kim Jeong Jin; Kang Hyuk; Kang Chulhun*; Kim Hwan Myung
来源:Chemical Communications, 2015, 51(12): 2407-2410.
DOI:10.1039/c4cc09416f

摘要

We report a two-photon fluorescent probe for ratiometric imaging of cysteamine in situ. This probe can detect the levels of endogenous cysteamine with statistical significance in live cells and brain hippocampal tissues, revealing that cysteamine is localized mainly in the perikaria of the pyramidal neurons and the granule cells.

  • 出版日期2015