Acute Otitis Media Replacement and Recurrence in the Finnish Otitis Media Vaccine Trial

作者:Jokinen Jukka*; Palmu Arto A; Kilpi Terhi
来源:Clinical Infectious Diseases, 2012, 55(12): 1673-1676.
DOI:10.1093/cid/cis799

摘要

We reanalyzed the 7-valent pneumococcal conjugate vaccine trial FinOM for prevention of acute otitis media (AOM), with a focus on disease replacement due to other pathogens and AOM recurrence. We found evidence of replacement disease occurring early during the trial follow-up and little vaccine impact on recurrent overall AOM episodes.

  • 出版日期2012-12-15