Acyl Protection Strategy for Synthesis of a Protic NHC Complex via N-Acyl Methanolysis

作者：Dobereiner Graham E; Chamberlin Catherine A; Schley Nathan D; Crabtree Robert H^*

来源：Organometallics, 2010, 29(21): 5728-5731.

DOI：10.1021/om100452g

In a new strategy for the synthesis of protic NHC complexes, iridium and rhodium complexes of N-benzoyl-substituted NHCs are first generated by direct deprotonation of an acyl-protected imidazolium salt. Deprotection of the acyl group with methanol then gives methyl benzoate and the protic NHC. This sequence represents a new strategy for the synthesis of protic NHC complexes. We expect this strategy to have useful generality.

• 出版日期2010-11-8