Autoimmune Hepatitis and Seronegative Hepatitis Associated With Myelodysplastic Syndrome in Children

作者:Rasmussen Line K*; Stenbog Elisabeth V; Kerndrup Gitte B; Hasle Henrik
来源:Journal of Pediatric Hematology/Oncology, 2016, 38(8): E274-E277.
DOI:10.1097/MPH.0000000000000651

摘要

An association between hepatitis and aplastic anemia (AA) is known as hepatitis-associated AA, and is characterized by an acute attack of hepatitis followed by the development of AA. We report 2 clinical cases of acute seronegative hepatitis in which pancytopenia with mild dysplasia developed after 3 months; however, neither of our cases fulfilled the histological criteria of AA, but rather myelodysplastic syndrome. This novel association bears considerable resemblance to hepatitis-associated AA, and raises the question of whether hepatitis-associated dysmyelopoiesis should be included in the spectrum of hypocellular myelodysplastic syndrome.

  • 出版日期2016-11