科研之友
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摘要
Aims Surgical ablation procedures for treating atrial. fibrillation have been shown to be highly successful. However, the ideal ablation pattern still remains to be determined. This article reports on a systematic study of the effectiveness of the performance of different ablation line patterns.
Methods and results This study of ablation tine patterns was performed in a biophysical model of human atria by combining basic lines: (i) in the right atrium: isthmus line, tine between vena cavae and appendage tine and (ii) in the left atrium: several versions of pulmonary vein isolation, connection of pulmonary veins, isthmus line, and appendage line. Success rates and the presence of residual atrial. flutter were documented. Basic patterns yielded conversion rates of only 10-25 and 10-55% in the right and the left atria, respectively. The best result for pulmonary vein isolation was obtained when a single closed tine encompassed all veins (55%). Combination of lines in the right/left atrium only Led to a success rate of 65/80%. Higher rates, up to 90-100%, could be obtained if right and left lines were combined. The inclusion of a left isthmus line was found to be essential for avoiding uncommon left atrial. flutter.
Conclusion Some patterns studied achieved a high conversion rate, although using a smaller number of tines than those of the Maze III procedure. The biophysical atrial model is shown to be effective in the search for promising alternative ablation strategies.
- 出版日期2007-11
