DigSee: disease gene search engine with evidence sentences (version cancer)

作者:Kim Jeongkyun; So Seongeun; Lee Hee Jin; Park Jong C; Kim Jung jae; Lee Hyunju
来源:Nucleic Acids Research, 2013, 41(W1): W510-W517.
DOI:10.1093/nar/gkt531

摘要

Biological events such as gene expression, regulation, phosphorylation, localization and protein catabolism play important roles in the development of diseases. Understanding the association between diseases and genes can be enhanced with the identification of involved biological events in this association. Although biological knowledge has been accumulated in several databases and can be accessed through the Web, there is no specialized Web tool yet allowing for a query into the relationship among diseases, genes and biological events. For this task, we developed DigSee to search MEDLINE abstracts for evidence sentences describing that %26apos;genes%26apos; are involved in the development of %26apos;cancer%26apos; through %26apos;biological events%26apos;. DigSee is available through http://gcancer.org/digsee.

  • 出版日期2013-7