A direct chemiluminescence method for the determination of prulifloxacin using tris-(4,7-diphenyl-1,10-phenanthrolinedisulfonic acid) ruthenium(II)-cerium(IV) system

作者：Cui Man; Yu Fengshan; Chen Fang; Chen Lanhua^*

来源：Analytical Letters, 2008, 41(11): 2001-2012.

DOI：10.1080/00032710802208690

• chemiluminescence
• cerium(IV)
• flow-injection
• prulifloxacin
• tris(4,7-diphenyl-1,10-phenanthrolinedisulfonic acid) ruthenium(II)

A simple, rapid, injection chemiluminescence method is described for the determination of prulifloxacin, a commonly used antibiotic. A strong chemiluminescence signal was detected when a mixture of the analyte and tris-(4,7-diphenyl-1,10-phenanthrolinedisulfonic acid)ruthenium(II) was injected into cerium(IV) sulfate. The chemiluminescence signal is proportional to the concentration of prulifloxacin in the range 4.0x10(-8) -9.0x10(-6) mol L(-1). The detection limit is 1.0x10(-8) mol L(-1), and the relative standard deviation is 2.2% (n=11) for the determination of 8.0x10(-7)mol L(-1) prulifloxacin. The proposed method was successfully applied to the determination of prulifloxacin in pharmaceutical preparations in capsules, spiked serum, and urine samples.

• 出版日期2008
• 单位南宁师范大学; 安徽大学; 华中科技大学