Hydrazonoyl halides in heterocycles: synthesis and anti-microbial activity of new 1,2,4-benzotriazine and bis-1,2,4-benzotriazine derivatives

作者：Mahran Asma M^*; Farghaly Thoraya A; Nada Afaf A

来源：Research on Chemical Intermediates, 2015, 41(5): 2961-2969.

DOI：10.1007/s11164-013-1404-9

• o-Dianisidine
• 1,2,4-Benzotriazine
• Bis-1,2,4-benzotriazine
• Hydrazonoyl halides
• Biological activity

Starting from o-dianisidine 1 or o-anisidine 7 with ethyl N-araylhydrazono chloroacetate 2a-d, a series of new 1,2,4-benzotriazine 4a-d, 9, and bis-1,2,4-benzotriazine 6a-d derivatives were prepared. The mechanisms of the studied reactions have been discussed and the anti-microbial activity of the isolated products has been evaluated.

• 出版日期2015-5