Microwave-accelerated Conjugate Addition of 2-Arylindoles to Substituted -Nitrostyrenes in the Presence of Ammonium Trifluoroacetate: An Efficient Approach for the Synthesis of a Novel Class of CB1 Cannabinoid Receptor Allosteric Modulators

作者：Kulkarni Pushkar M; Ranade Ameya; Garai Sumanta; Thakur Ganesh A

来源：Journal of Heterocyclic Chemistry, 2017, 54(3): 2079-2084.

DOI：10.1002/jhet.2861

2‐Arylindoles, in general, exhibit reduced reactivity towards the conjugate addition to substituted nitrostyrenes, when compared with indoles. We report here an efficient, expeditious, and high‐yielding conjugate addition of 2‐arylindoles to substituted β‐nitrostyrenes in the presence of ammonium tr...

• 出版日期2017-5
• 单位Northeastern university; 东北大学