Accuracy of MIC determination for Streptococcus pneumoniae using the Sirscan2000automatic MIC determination system

作者：Grohs Patrick^*; Janoir Claire; Grondin Sophie; Simon Sylvie; Bonnet Gaelle; Henry Laura; Gutmann Laurent; Varon Emmanuelle

来源：Diagnostic Microbiology and Infectious Disease, 2011, 70(3): 399-403.

DOI：10.1016/j.diagmicrobio.2011.03.005

• Streptococcus pneumoniae
• MIC
• Agar determination
• Automate
• Sirscan

The Sirscan2000automatic MIC determination (SIR-MD) system is a new system for MIC determination based on the automatic detection of growth of bacteria spotted onto agar medium using a camera scan. To evaluate its accuracy, 3608 Streptococcus pneumoniae clinical isolates yielding 18,165 MICs were tested in parallel with the SIR-MD and a standard interpretive antibiogram procedure. The overall percent agreement between the 2 methods within 1 log(2) dilution was 86.9%. After exclusion of the 11.8% noninterpretable results, errors in the deduction of susceptibilities were very major in 0.03%, major in 0.2%, and minor in 1.3%.

• 出版日期2011-7