A membrane permeable fluorescent Ca2+ probe based on bis-BODIPY with branched PEG

作者:Duan Wenfeng; Wei Huimin; Cui Tengbo; Gao Baoxiang*
来源:Journal of Materials Chemistry B, 2015, 3(5): 894-898.
DOI:10.1039/c4tb01457j

摘要

A new class of Ca2+ probes is developed based on PEG-BODIPY-BAPTA conjugates. These newly formed probes with BAPTA acid exhibit high sensitivity and selectivity for Ca2+ over other metal ions, can pass through the cell membranes of living cells without special procedures, and can monitor changes in the intracellular Ca2+ signal.