Automated and fast building of three-dimensional RNA structures

作者：Zhao Yunjie; Huang Yangyu; Gong Zhou; Wang Yanjie; Man Jianfen; Xiao Yi^*

来源：Scientific Reports, 2012, 2: 734.

DOI：10.1038/srep00734

Building tertiary structures of non-coding RNA is required to understand their functions and design new molecules. Current algorithms of RNA tertiary structure prediction give satisfactory accuracy only for small size and simple topology and many of them need manual manipulation. Here, we present an automated and fast program,3dRNA, for RNA tertiary structure prediction with reasonable accuracy for RNAs of larger size and complex topology.

• 出版日期2012-10-15
• 单位华中科技大学