ANVAYA: A WORKFLOWS ENVIRONMENT FOR AUTOMATED GENOME ANALYSIS

作者：Limaye Bhakti^*; Banerjee Ruma; Datta Avik; Inamdar Harshal; Vats Pankaj; Dahale Sonal; Bhandari Alok; Ramakrishnan E P; Tupakula Rajnikanth; Malviya Sandeep; Bayaskar Avinash; Gadhari Renu; Jain Sankalp; Gavane Vivek; Mahajan Rashmi; Sunitha K; Joshi Rajendra

来源：Journal of Bioinformatics and Computational Biology, 2012, 10(4): 1250006.

DOI：10.1142/S0219720012500060

• Bioinformatics
• workflow
• genome analysis
• HPC
• automated pipeline

Anvaya is a workflow environment for automated genome analysis that provides an interface for several bioinformatics tools and databases, loosely coupled together in a coordinated system, enabling the execution of a set of analyses tools in series or in parallel. It is a client-server workflow environment that has an advantage over existing software as it enables extensive pre & post processing of biological data in an efficient manner. "Anvaya" offers the user, novel functionalities to carry out exhaustive comparative analysis via "custom tools," which are tools with new functionality not available in standard tools, and "built-in PERL parsers," which automate data-flow between tools that hitherto, required manual intervention. It also provides a set of 11 pre-defined workflows for frequently used pipelines in genome annotation and comparative genomics ranging from EST assembly and annotation to phylogenetic reconstruction and microarray analysis. It provides a platform that serves as a single-stop solution for biologists to carry out hassle-free and comprehensive analysis, without being bothered about the nuances involved in tool installation, command line parameters, format conversions required to connect tools and manage/process multiple data sets at a single instance.

• 出版日期2012-8