Magnetically Encoded Luminescent Composite Nanoparticles through Layer-by-Layer Self-Assembly

作者：Song Erqun^*; Han Weiye; Xu Hongyan; Jiang Yunfei; Cheng Dan; Song Yang; Swihart Mark T

来源：Chemistry - A European Journal, 2014, 20(45): 14642-14649.

DOI：10.1002/chem.201403699

• luminescence
• magnetic properties
• nanoparticles
• quantum dots
• self-assembly

Sensitive and rapid detection of multiple analytes and the collection of components from complex samples are important in fields ranging from bioassays/chemical assays, clinical diagnosis, to environmental monitoring. A convenient strategy for creating magnetically encoded luminescent CdTe@ SiO2@ nFe(3)O(4) composite nanoparticles, by using a layer-by-layer self-assembly approach based on electrostatic interactions, is described. Silica-coated CdTe quantum dots (CdTe@ SiO2) serve as core templates for the deposition of alternating layers of Fe3O4 magnetic nanoparticles and poly(dimethyldiallyl ammonium chloride), to construct CdTe@ SiO2@ nFe(3)O(4) (n= 1, 2, 3,.) composite nanoparticles with a defined number (n) of Fe3O4 layers. Composite nanoparticles were characterized by zeta-potential analysis, fluorescence spectroscopy, vibrating sample magnetometry, and transmission electron microscopy, which showed that the CdTe@ SiO2@ nFe(3)O(4) composite nanoparticles exhibited excellent luminescence properties coupled with well-defined magnetic responses. To demonstrate the utility of these magnetically encoded nanoparticles for near-simultaneous detection and separation of multiple components from complex samples, three different fluorescently labeled IgG proteins, as model targets, were identified and collected from a mixture by using the CdTe@ SiO2@ nFe(3)O(4) nanoparticles.

• 出版日期2014-11-3
• 单位西南大学