Lyme disease with lymphocytic meningitis, trigeminal palsy and silent thalamic lesion

作者：Koechling Joachim; Freitag Hans J; Bollinger Thomas; Herz Alexander; Sperner Juergen

来源：European Journal of Paediatric Neurology, 2008, 12(6): 501-504.

DOI：10.1016/j.ejpn.2007.11.009

• Neuroborreliosis
• Trigeminal nerve palsy
• Thalamic lesion
• MRI
• Follow-up report

We describe a follow-up in a 15-year-old boy with neuroborreliosis diagnosed by clinical symptoms, CSF and serum analysis. MRI revealed a thalamic lesion and an enhancement of the right trigeminal nerve clinically associated with mild hypasthesia in the right maxillary region. Both, clinical symptoms and radiological findings disappeared within 2 months after treatment. Borrelia burgdorferi specific IgM and IgG in CSF and IgG in serum became negative between 6 and 12 months after diagnosis. We show that neuroborreliosis at an early stage may present only with moderate neurological deficits and that at this stage MRI reveals distinct cerebral lesions which might even precede clinical manifestation. Thus, early diagnosis and treatment of neuroborreliosis may prevent persistent neurologic lesions.

• 出版日期2008-11
• 单位河北医科大学