A rapid and convenient synthesis of gem-bis(dithiocarbamate) derivatives from primary aliphatic amines, carbon disulfide, and aromatic aldehydes using boron trifluoride-diethyl etherate

作者：Nemati Firouzeh^*; Ghiyaei Ali Ghorbani Gharjeh; Notash Behrouz; Shayegan Mojtaba Hajiloo; Amani Vahid

来源：Tetrahedron Letters, 2014, 55(25): 3572-3575.

DOI：10.1016/j.tetlet.2014.04.106

• Dithiocarbamic acid salt
• Primary aliphatic amine
• Carbon disulfide
• Boron trifluoride-diethyl etherate

An efficient route for the synthesis of gem-bis(dithiocarbamate) derivatives is developed using dithiocarbamic acid salts generated from primary aliphatic amines and CS2. The method offers high yields, employs mild reaction conditions, and demonstrates excellent functional group compatibility. The structures of the products were confirmed spectroscopically and by X-ray analysis.

• 出版日期2014-6-18