A concise approach to (+)-1-epi-castanospermine

作者：Wu Tian Jun; Huang Pei Qiang^*

来源：Tetrahedron Letters, 2008, 49(2): 383-386.

DOI：10.1016/j.tetlet.2007.11.033

• castanospermine
• tetramic acid
• synthon
• Mukaiyama type reaction

A concise enantioselective synthesis of (+)-1-epi-castanospermine (2) is described, which featured the use of chiral non-racemic tetramic acid derivative 5 as a synthetic equivalent of the challenging synthon A through a highly diastereoselective vinylogous Mukaiyama type reaction.

• 出版日期2008-1-7
• 单位厦门大学