Asthma in women

作者：Semjen C Raherison^*

来源：Revue Francaise d'Allergologie, 2013, 53(3): 205-207.

DOI：10.1016/j.reval.2013.01.029

• Asthma
• Women
• Lung function
• Allergy
• Sex hormones
• Estrogen

Asthma is more prevalent among boys than girls; this relationship is reversed on reaching puberty. The literature gives several indications that hormonal and metabolic factors play a role in the development of asthma in women and an impact on their lung function, but the pathophysiology remains unclear. Endogenous hormone levels vary according to menarche, menstrual phase, menstrual irregularity, pregnancy, lactation and proximity to menopause; sex hormone levels might also vary according to other metabolic factors, such as obesity. Asthma is more frequent and severe in women after puberty. Asthma exacerbations seem to be associated with menstrual cycle variations; irregular menstruation and menopausal transitions are associated with an increased risk of incident asthma and a decrease in lung function.

• 出版日期2013-4