Directed Metalation Cascade To Access Highly Functionalized Thieno[2,3-f]benzofuran and Exploration as Building Blocks for Organic Electronics

作者：Aeschi, Yves; Li, Hui; Cao, Zhencai; Chen, Songjie; Amacher, Anneliese; Bieri, Nathalie; Oezen, Bilal; Hauser, Juerg; Decurtins, Silvio; Tan, Songting; Liu, Shi Xia^*

来源：Organic Letters, 2013, 15(21): 5586-5589.

DOI：10.1021/ol402787d

A tandem directed metalation has been successfully applied to the preparation of thieno[2,3-f]benzofuran-4,8-dione, providing an efficient and facile approach to symmetrically and unsymmetrically functionalize the thieno[2,3-f]benzofuran core at the 2,6 positions as well as to introduce the electron-withdrawing or -donating groups (EWG or EDG) at its 4,8 positions. The presence of various functional groups makes late-stage derivatization attainable.

• 出版日期2013-11-1
• 单位湘潭大学