Alternative translation initiation in immunity: MAVS learns new tricks

作者:Ivanov Pavel*; Anderson Paul
来源:Trends in Immunology, 2014, 35(5): 188-189.
DOI:10.1016/j.it.2014.03.005

摘要

Translational control of gene expression contributes to various aspects of immune function [1]. Recent results by Brubaker et al. [2] show how alternative translation initiation produces distinct isoforms of Mitochondrial Antiviral Signaling (MAVS), an adaptor protein associated with RIG-I and MDA5 that possess unique immunomodulatory properties.

  • 出版日期2014-5

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