科研之友
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摘要
Hemiarthroplasty is a potentially attractive alternative to knee replacement for young, active patients, as it allows preservation of more bone stock for potential revisions. However, there has been limited success with hemiarthroplasty or spacers to date. The wear and degradation of the biomaterial-cartilage interface is of paramount importance in the design and success of hemiarthroplasties. A comprehensive understanding of the tribological performance of hemiarthroplasty implants in the natural joint is required. The objective of this study was to investigate the tribological response of bovine medial compartmental knees, both natural and hemiarthroplasty replaced, under physiological loads and motion. The conformity of these metallic hemi arthroplasties was varied (conforming plates with radius of 50 mm and radius of 100 mm and a flat plate design), in order to examine the effects of conformity and contact stress, on the friction, friction shear stress and cartilage degeneration. With decreasing conformity of hemiarthroplasty bearings, an increase in contact stress was found, which resulted in elevated friction, elevated friction shear stress and increased cartilage degeneration. A strong correlation was found between contact stress and wear and between friction shear stress and wear. This new and unique in vitro tribological simulation has shown the direct elevation of friction, surface fibrillation and biomechanical wear of cartilage, upon replacing the tibia with a hemiarthroplasty, particularly when using low conformity hemiarthroplasty designs.
- 出版日期2009-6-19
- 单位河北医科大学
