Anatomical Segregation of Visual Selection Mechanisms in Human Parietal Cortex

作者:Capotosto Paolo*; Tosoni Annalisa; Spadone Sara; Sestieri Carlo; Perrucci Mauro Gianni; Romani Gian Luca; Della Penna Stefania; Corbetta Maurizio
来源:Journal of Neuroscience, 2013, 33(14): 6225-6229.
DOI:10.1523/JNEUROSCI.4983-12.2013

摘要

Visual selection requires mechanisms for representing object salience and for shifting the focus of processing to novel objects. It is not clear from computational or neural models whether these operations are performed within the same or different brain regions. Here, we use repetitive transcranial magnetic stimulation to briefly interfere with neural activity in individually localized regions of human posterior parietal cortex (PPC) that are putatively involved in attending to contralateral locations or shifting attention between locations. Stimulation over right ventral intraparietal sulcus impaired target discrimination at contralateral locations, whereas stimulation over right medial superior parietal lobule impaired target discrimination after a shift of attention regardless of its location. This double dissociation is consistent with neuroimaging studies and indicates that mechanisms of visual selection are partly anatomically segregated in human PPC.

  • 出版日期2013-4-3