An Integrative Quantitative Model of Factors Influencing the Course of Anorexia Nervosa Over Time

作者：Yackobovitch Gavan Michal; Golan Moria; Valevski Avi; Kreitler Shulamit; Bachar Eytan; Lieblich Amia; Mitrani Edith; Weizman Abraham; Stein Daniel^*

来源：International Journal of Eating Disorders, 2009, 42(4): 306-317.

DOI：10.1002/eat.20624

• anorexia nervosa
• remission
• anxiety
• obsessionality

Objective: To identify factors influencing the course of anorexia nervosa (AN) over time.
Method: Former female patients with AN (36 remitted and 24 nonremitted) and 31 healthy females responded to standardized interviews and self-rating questionnaires. Remitted patients maintained normal eating, normal weight, and regular menses for the past 12 months. Patients not fulfilling these criteria were considered nonremitted.
Results: Using logistic regression, we identified that number of hospitalizations, duration of ambulatory treatment, past vegetarianism, past anxiety, and childhood sexual abuse differentiated remitted from nonremitted patients, predicting nonremission. A similar analysis identified that elevated follow-up vegetarianism and eating-related concerns and lower body mass index (BMI) differentiated remitted from nonremitted patients, contributing to nonremission. Univariate analyses identified that remitted patients had elevated anxiety and eating-related obsessionality compared with the controls, suggesting these variables to potentially predispose to AN.
Discussion: Elevated anxiety and eating-related obsessionality may increase the risk for the development of AN and for nonremission.

• 出版日期2009-5
• 单位上海市精神卫生中心