Acute disseminated encephalomyelitis associated with hepatitis B virus reinfection - Consequence or coincidence?

作者：Lazibat Ines^*; Brinar Vesna

来源：Clinical Neurology and Neurosurgery, 2013, 115: S35-S37.

DOI：10.1016/j.clineuro.2013.09.018

• Acute disseminated encephalomyelitis (ADEM)
• Hepatitis B virus (HBV)
• Recurrent and multiphasic forms of DEM

Acute disseminated encephalomyelitis (ADEM) is an idiopathic inflammatory demyelinating disease of the CNS that is particularly difficult to differentiate from the first episode of multiple sclerosis. ADEM typically occurs as a post-infectious phenomenon, and usually presents a monophasic episode, but also includes recurrent and multiphasic forms. We report a case of ADEM associated with hepatitis B virus (HBV) reinfection. After steroid and IV immunoglobulin treatment, neurologic symptoms were improved. We suppose that the HBV reinfection was the cause of ADEM, but possible pathogenetic mechanism is still obscure.

• 出版日期2013-12