科研之友
微信
新浪微博
Facebook
分享链接
摘要
Coronary spasm can usually be controlled by administration of Ca antagonists. However. there are some cases of coronary spasm whose attacks cannot be controlled even with large doses of Ca antagonist and/or its combination with nitrates Here we describe the case of a 41-year-old man whose attacks of coronary spasm were resistant to the combined administration of nitrates, Ca antagonists. and a statin The attacks were all and disappeared after withdrawal of nitrates and recurred after readministration of a nitroglycerin patch The involvement of nitrate tolerance in the pathogenesis of multidrug resistant coronary spasm was revealed and its implication discussed (Int Heart J 2010, 51 211-213)
- 出版日期2010-5
