Amperometric determination of omeprazole on screen-printed electrodes using batch injection analysis

作者：Stefano Jessica S; Tormin Thiago F; da Silva Jamilia P; Richter Eduardo M; Munoz Rodrigo A A^*

来源：Microchemical Journal, 2017, 133: 398-403.

DOI：10.1016/j.microc.2017.04.007

• Amperometry
• Multiwalled carbon nanotube
• Flow-injection analysis
• Pharmaceutical formulations

This work demonstrates the sensitive amperometric determination of omeprazole on screen-printed electrodes (SPE) using batch-injection analysis (BIA). A SPE containing a multiwalled carbon nanotube modified electrode coupled to the BIA system provided an analytical method with a low detection limit (9 nmol L-1), high precision (13%) and sample throughput (120 h(-1)), employing microliter sample volumes injected by an electronic micro pipette. The full analytical system presents portable characteristics that enable application for on-site analysis. Analytical results for pharmaceutical samples analyzed by the proposed method were in agreement with those obtained by spectrophotometry. Moreover, the BIA method presented advantages over the flow-injection analysis with amperometric detection such as detection limit, sensitivity, and sample throughput.

• 出版日期2017-7