Development of a New 4-Amino-1,8-Naphthalimide Derivative as a Fluorescent Probe for Monitoring the Divalent Copper Ion

作者：Shen, Kesheng; Mao, Shanshan; Shi, Xinkui; Aderinto, Stephen Opeyemi; Xu, Yuling; Wu, Huilu^*

来源：Journal of Applied Spectroscopy, 2018, 85(4): 665-672.

DOI：10.1007/s10812-018-0702-9

• 4-amino-1,8-naphthalimide
• fluorescent probe
• divalent copper ion
• synthesis

This article presents the design and synthesis of a new variant of the 4-amino-1,8-naphthalimide fluorescent probe for monitoring the divalent copper ion, Cu2+. The probe BRST, functionalized with two propionic carboxylic acid groups in its receptor moiety, demonstrated high selectivity and sensitivity for the detection of Cu2+ in competitive media of various metal ions in DMSO/HEPES buffer solution (1:1; pH 7.4), with a fluorescence quenching of 75.41%. Besides its good linearity with Cu2+, the probe yielded commendable values of the association constant and the detection limit, 5.54 x 10(5) M-1 and 4.33 x 10(-9) M, respectively. The quenching of the fluorescence intensity of the sensor in the presence of Cu2+ ions is attributable to the strong paramagnetic nature of the Cu2+ ion. The fluorescence "turn off" behavior of this simple and effective probe was successfully applied for the determination of Cu2+ levels in untreated water samples, with excellent recovery rates of 98-105.8%.

• 出版日期2018-9
• 单位兰州交通大学