A practical approach for regioselective mono-nitration of phenols under mild conditions

作者：Chen, Ling-Yan; Liu, Tao; Zhou, Xiaokun; Sun, Zhihua^*

来源：ARKIVOC, 2014, 2014(5): 64-71.

DOI：10.3998/ark.5550190.p008.587

• Nitration
• regioselective
• metal nitrates
• phenolic compounds

Cu(NO3)(2)center dot 3H(2)O was demonstrated to be an efficient, regioselective and inexpensive nitrating reagent for the synthesis of mono-nitro substituted phenolic compounds. 12 examples of different phenols were examined. Good yields (67-90%) have been achieved.

• 出版日期2014
• 单位上海工程技术大学