A water-soluble conjugated polymer with azobenzol side chains based on %26quot;turn-on%26quot; effect for hypoxic cell imaging

作者:Li Jie; Yuan Yan; Zeng Gaoshan; Li Xiang; Yang Zhen; Li Xiaozhen; Jiang Rongcui; Hu Wenbo; Sun Pengfei; Wang Qi; Lu Xiaomei; Fan Quli; Huang Wei
来源:Polymer Chemistry, 2016, 7(45): 6890-6894.
DOI:10.1039/c6py01567k

摘要

A water-soluble conjugated polymer (WSCP) with enzymatic cleavable linkages (azobenzene) side chains for hypoxia imaging is reported. The fluorescence of the polymer would be recovered as the azobenzene moieties cleaved in hypoxia. This conjugated polymer was proved to be a good hypoxic sensor.