Beyond metaphor: contrasting mechanisms of social and physical pain

作者：Iannetti Gian Domenico^*; Salomons Tim V; Moayedi Massieh; Mouraux Andre; Davis Karen D

来源：Trends in Cognitive Sciences, 2013, 17(8): 371-378.

DOI：10.1016/j.tics.2013.06.002

• nociception
• pain
• functional brain imaging
• reverse inference
• social rejection
• multivariate pattern analysis

Physical pain can be clearly distinguished from other states of distress. In recent years, however, the notion that social distress is experienced as physically painful has permeated the scientific literature and popular media. This conclusion is based on the overlap of brain regions that respond to nociceptive input and sociocultural distress. Here we challenge the assumption that underlies this conclusion that physical pain can be easily inferred from a particular pattern of activated brain regions by showing that patterns of activation commonly presumed to constitute the %26apos;pain matrix%26apos; are largely unspecific to pain. We then examine recent analytical advances that may improve the specificity of imaging for parsing pain from a broad range of perceptually unique human experiences.

• 出版日期2013-8
• 单位河北医科大学