Molecular Typing of Acinetobacter baumannii Isolated from Chinese Intensive Care Units Before and After the 2008 Sichuan Earthquake

作者：Xie Y; Kang M^*; He C; Guo L; Chen C; Fan H

来源：Laboratory Medicine, 2013, 44(1): 40-45.

DOI：10.1309/LM6GV70JDKYTHWDY

• A baumannii
• earthquake
• nosocomial infection
• resistance
• rep-PCR

Objective: To trace the spread of Acinetobacter baumannii in intensive care units (ICUs) before and after the 2008 Sichuan earthquake in China.
Methods: A baumannii strains were collected between July and October 2007 from control patients and in May 2008 from survivors of the Sichuan earthquake. The multidrug resistance profile of A baumannii was observed. The DiversiLab semi-automated rep-PCR system was used to determine the clonal relatedness of A baumannii strains; testing for antimicrobial susceptibility was performed using automated instruments.
Results: A total of 28 A baumannii strains were isolated, 13 of which had been isolated from control patients; 15 strains were isolated from earthquake survivors. Regardless of patient group, 2 clonal groups were observed in these isolates. The results demonstrate that most Of the A baumannii isolates recovered from the earthquake survivors were similar to those obtained from the control patients. This suggests that A baumannii species, particularly those of clonal groups A and B (most of which are multidrug-resistant [MDR]), have been well established in our ICU; that earthquake survivors probably acquired A baumannii in the hospital setting; and that A baumannii recovered from earthquake survivors may bring different genetic profiles into contact with local isolates.
Conclusions: Our findings highlight the need for stronger infection-control measures and emphasize the importance of rapid strain typing for monitoring pathogens such as A baumannii that are frequently associated with nosocomial infections.

• 出版日期2013
• 单位四川大学