Assessment of additional endpoints for trials in acute stroke - what, when, where, in who?

作者:Schellinger Peter D*; Bath Philip M W; Lees Kennedy R; Bornstein Natan M; Uriel Eitan; Eisert Wolfgang; Leys Didier
来源:International Journal of Stroke, 2012, 7(3): 227-230.
DOI:10.1111/j.1747-4949.2012.00773.x

摘要

Functional outcome in acute stroke trials among others is usually measured on the modified Rankin Scale. However, new onset of depression, cognitive decline, and communication deficits alone or in combination affect more than 25% of patients. This report summarizes the findings and conclusions of a workshop by the European Stroke Organization held in February 2011 We propose that assessment of mood disorders, cognitive impairment/dementia, language or communication dysfunction, and quality of life should supplement outcome measures after acute stroke.

  • 出版日期2012-4