An efficient synthesis of 2-hydroxy-7,8-dihydroquinolin-5(6H)-ones and 7,8-dihydroquinoline-2,5(1H,6H)-diones from Morita-Baylis-Hillman adduct acetates

作者：Zhong Weihui^*; Lin Fuliang; Chen Ren'er; Su Weike

来源：Synthesis, 2008, (16): 2561-2568.

DOI：10.1055/s-2008-1078601

• 2-hydroxy-7,8-dihydroquinolin-5(6H)-ones
• 7,8-dihydroquinoline-2,5(1H,6H)-diones
• Morita-Baylis-Hillman adduct acetates
• cyclohexane-1,3-diones
• solvent-free conditions

A series of 2-hydroxy-7,8-dihydroquinolin-5(6H)-ones and 7,8-dihydroquinoline-2,5(1H,6H)-diones have been synthesized in good to excellent yields from Morita-Baylis-Hillman adduct acetates, cyclohexane-1,3-diones and ammonium acetate or primary amines in one pot under solvent-free conditions.

• 单位
  浙江工业大学