Novel isolation of acetophenone derivatives with spiroketal-hexosefuranoside in Upuna borneensis

作者：Ito Tetsuro^*; Ito Hiromi; Oyama Masayoshi; Tanaka Toshiyuki; Murata Jin; Darnaedi Dedy; Iinuma Munekazu

来源：Phytochemistry Letters, 2012, 5(2): 325-328.

DOI：10.1016/j.phytol.2012.02.012

• Upuna borneensis Sym.
• Dipterocarpaceae
• 4 ',5 '-Dihydrospiro[benzofuran-2(3H),2 '(3 ' H)-furan]
• Upuborneol A
• Upuborneol B

Our investigations of the chemical constituents in the leaves of Upuna borneensis Sym. (Dipterocarpaceae) resulted in the isolation of two novel diastereomeric acetophenone derivatives, upuborneols A (1) and B (2), along with four known derivatives (3-6). Their structures were determined by spectroscopic analysis including two-dimensional NMR and the speculation of biogenesis. Compounds 1 and 2 had a C-6 unit derived from sugar unit and are the first known representatives of natural acetophenone derivatives bearing a spiroketal moiety.

• 出版日期2012-6