Miniaturized Optical Resolution Photoacoustic Microscope Based on a Microelectromechanical Systems Scanning Mirror

作者：Qi, Weizhi; Chen, Qian; Guo, Heng; Xie, Huikai; Xi, Lei^*

来源：Micromachines, 2018, 9(6): 288.

DOI：10.3390/mi9060288

• photoacoustic
• microelectromechanical systems (MEMS)
• miniaturized microscope

In this paper, we report a miniaturized optical resolution photoacoustic microscopy system based on a microelectromechanical system (MEMS) scanning mirror. A two-dimensional MEMS scanning mirror was used to achieve raster scanning of the excitation optical focus. The wideband photoacoustic signals were detected by a flat ultrasound transducer with a center frequency of 10 MHz and an active area of 2 mm in diameter. The size and weight of this device were 60 mm x 30 mm x 20 mm and 40 g, respectively. We evaluated this system using sharp blades, carbon fibers, and a silver strip target. In vivo experiments of imaging vasculatures in the mouse ear, brain, and human lip were completed to demonstrate its potential for biological and clinical applications.

• 出版日期2018-6
• 单位电子科技大学