Antioxidant and Antimicrobial Phenolic Compounds from Setaria viridis

作者：Fan, Lu; Ma, Jie; Chen, Yan-Hua; Chen, Xuan-Qin^*

来源：Chemistry of Natural Compounds, 2014, 50(3): 433-437.

DOI：10.1007/s10600-014-0979-8

• Setaria viridis
• phenolic compounds
• antioxidant activity
• antimicrobial activity

A chemical study of the 80% aqueous acetone extract of aerial parts of Setaria viridis led to the isolation of three new naphthol rhamnosides, 8-O-alpha-L-rhamnosyl-beta-sorigenin (1), 6-hydroxy-8-O-alpha-L-rhamnosyl-beta-sorigenin (2), and 6-methoxy-8-O-alpha-L-rhamnosyl-beta-sorigenin (3), together with nine (4-12) known compounds. Their structures were established on the basis of spectroscopic data, including IR, MS, 1D, and 2D NMR. All the 12 compounds were tested for their antioxidant activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals, as well as antimicrobial activity. Compounds 1-3 exhibited strong antioxidant activity with IC50 values of 10.5, 13.8, and 15.3 mu M, respectively, and modest activity against Staphylococcus aureus (ATCC 29213).

• 出版日期2014-7
• 单位云南省疾病预防控制中心; 昆明理工大学; 云南大学