A novel biphenyl-derived salicylhydrazone Schiff base fluorescent probes for identification of Cu2+ and application in living cells

作者：Yang, Yun-Shang^*; Ma, Suo-Suo; Zhang, Ying-Peng^*; Ru, Jia-Xi; Liu, Xiao-Yu; Guo, Hui-Chen

来源：Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy , 2018, 199: 202-208.

DOI：10.1016/j.saa.2018.03.060

• Salicylhydrazone Schiff base
• Fluorescence
• Identification
• Cu2+

A novel biphenyl-derived salicylhydrazone Schiff base (BSS) fluorescent probes for highly sensitive and selective identification of Cu2+ has been synthesized. In addition, the recognition has been proved experimentally. The results indicated that the complex forms a 1:1 complex with Cu2+ shows fluorescent quenching. Furthermore, the detection limit of 1.54 x 10(-8) M. More interesting, the probe BSS not only have a good biocompatibility in living cells, but also the sense behavior of Cu2+ in the cell nucleus.

• 出版日期2018-6-15
• 单位中国农业科学院; 兰州理工大学; 中国农业科学院兰州兽医研究所; 家畜疫病病原生物学国家重点实验室