Antimicrobial Effect of a Crude Sulfated Polysaccharide from the Red Seaweed Gracilaria ornata

作者：dos Santos Amorim Rodrigo das Neves; Gurgel Rodrigues Jose Arievilo; Holanda Marjory Lima; Gomes Quindere Ana Luiza; Monteiro de Paula Regina Celia; Maciel Melo Vania Maria; Barros Benevides Norma Maria

来源：Brazilian Archives of Biology and Technology, 2012, 55(2): 171-181.

• Rhodophyta
• sulfated macromolecules
• chemical analysis
• antimicrobial

The aim of this study was to determine the yield, chemical composition, specific rotation (SR), infrared (IR) spectroscopy and the effect on bacterial growth of a crude sulfated polysaccharide (SP) from the red marine alga G. ornata (Go). Go-1 (25 degrees C), Go-2 (80 degrees C), and Go-3 (80 degrees C) were sequentially extracted and yielded 9.2%. The contents of sulfate (5.88-10.3%) and proteins (0.1-3.7%) were small. The values of SR were [proportional to](D)(20 degrees f) -19.0, -51.0, and -56.5, respectively. IR spectrums showed the presence of galactose-4 sulfate and absence of 3,6-anydrogalactose-2 sulfate, galactose-6 sulfate and galactose-2 sulfate. SR and IR techniques confirmed SPs. Go-3 was tested on the growth of bacteria (Bacillus subtilis, Staphylococcus aureus, Enterobacter aerogens, Escherichia coli, Pseudomonas aeruginosa, Salmonela choleraesuis and Salmonela typhi), but only E. coli was inhibited.

• 出版日期2012-4