Analysis of Risk Factors for Vascular Cognitive Impairment in Patients with Cerebral Infarction

作者：An Xiao lei^*; Li Chuan ling

来源：Cell Biochemistry and Biophysics, 2015, 71(2): 673-677.

DOI：10.1007/s12013-014-0246-4

• Cerebral infarction
• Vascular cognitive impairment
• Risk factors
• Multivariate logistic regression analysis
• Montreal cognitive assessment

This study aimed to identify risk factors for vascular cognitive impairment (VCI) in cerebral infarction patients. Associations between VCI and age, gender, blood pressure, lipid levels, glycosylated hemoglobin, atrial fibrillation, tobacco smoking, alcohol consumption, homocysteine (Hcy), and High-Sensitivity C-Reactive Protein (HS-CRP) were evaluated in patients with cerebral infarction (n = 300) using single factor analysis and multivariate logistic regression analysis. By single factor analysis, the age, glycosylated hemoglobin, atrial fibrillation, blood pressure, Hcy, HS-CRP, tobacco smoking, and alcohol consumption were significantly associated with VCI in these patients. By multivariate logistic regression analysis, the age, glycosylated hemoglobin, blood pressure, Hcy, and HS-CRP were revealed as independent risk factors. The age, glycosylated hemoglobin, blood pressure, Hcy, and HS-CRP can serve as predictive factors for VCI in patients with cerebral infarction.

• 出版日期2015-3